Prostate Cancer Secrets

Decipher Prostate Biopsy Report Explained

The test report for the Decipher Prostate Biopsy provides a three-tiered Decipher genomic score reflecting the tumor’s biological risk for distant…

Sep 23 • 

Keith R. Holden, M.D.

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Seven Essentials: What a 22-Gene Decipher Score Means For You - 067

A test called a Decipher Genomic Classifier is shedding light on the heterogeneity of prostate cancer, offering a clearer picture by analyzing the…

Sep 10 • 

Keith R. Holden, M.D.

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August 2025

Why Men Struggle With Active Surveillance and How to Help Them - 066

Your doctor just told you that you have prostate cancer. Then they tell you the best plan is to monitor it. This is the reality for thousands of men…

Aug 22 • 

Keith R. Holden, M.D.

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July 2025

My Latest Lab Results - 065

There was the usual low-grade anxiousness in the past two weeks, which is typical for me in the lead-up to getting lab results, specifically, PSAnxiety.

Jul 29 • 

Keith R. Holden, M.D.

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Shared Decision-Making in Prostate Cancer Screening - 064

Despite prostate cancer being one of the most common causes of cancer in men, prostate cancer screening with the prostate-specific antigen (PSA) blood…

Jul 9 • 

Keith R. Holden, M.D.

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June 2025

Rebuttal to “What’s the Truth About Prostate Cancer?” - 063

This newsletter is a rebuttal to an article, “What’s the Truth About Prostate Cancer,” an article framing the entire field of prostate cancer management…

Jun 10 • 

Keith R. Holden, M.D.

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May 2025

Multiparametric MRI for Prostate Cancer - 062

Multiparametric magnetic resonance imaging (mpMRI) is a special type of scan that combines several different imaging techniques to create detailed…

May 22 • 

Keith R. Holden, M.D.

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My Shocking PSA Results - 061

It had been six months since my last prostate-specific antigen (PSA) level, and I knew it was time for another set of labs.

May 5 • 

Keith R. Holden, M.D.

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April 2025

Liquid Biomarkers Guide Smarter Prostate Cancer Screening- 060

These blood or urine tests add detail to the PSA picture, helping to answer the question: Is this something we need to act on right now, or can we…

Apr 22 • 

Keith R. Holden, M.D.

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I Had Such High Hopes for Pluvicto - 059

Pluvicto is a precision type of radiation in which a radioisotope is injected into the bloodstream. The radioisotope then locates and binds to the PSMA…

Apr 7 • 

Keith R. Holden, M.D.

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March 2025

Using AI to Understand Prostate Cancer - 058

This newsletter is a video about how I use Google NotebookLM to research and understand prostate cancer.

Mar 24 • 

Keith R. Holden, M.D.

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Here's Your Gift For Being a Paid Subscriber

Thank you!

Mar 10 • 

Keith R. Holden, M.D.