Prostate Cancer Secrets

My Latest PET Scan Results - 76

Before I tell you what my latest PET scan shows and what our plan is, I want to provide a quick reminder of how we got here.

Aug 1 • Keith R. Holden, M.D.

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May 2026

Turning The Lens On My Own DNA- 075

I used 23andMe, a free genetic analysis tool, and Claude AI to uncover three genetic variants that may have contributed to my diagnosis. Here's what I'm…

May 29 • Keith R. Holden, M.D.

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I Was Hospitalized - 074

Before I tell you about my hospitalization, I need to tell you about my latest lab results.

May 1 • Keith R. Holden, M.D.

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April 2026

How To Manage PSA Anxiety - 073

I use the term ‘PSAnxiety’ because I was noticing that every time it came around, the time for me to recheck my PSA, I would start feeling this…

Apr 9 • Keith R. Holden, M.D.

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March 2026

When Your Prostate Cancer Drug Becomes Cancer Fuel - 072

Prostate cancer is a trickster

Mar 20 • Keith R. Holden, M.D.

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February 2026

December 2025

Understanding Decipher GRID For Prostate Cancer - 070

The Decipher Prostate Genomic Classifier is the clinical product, but it is derived from the Decipher Genomic Resource Information Database (Decipher…

Dec 29, 2025 • Keith R. Holden, M.D.

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Decoding Cancer with Keith Holden MD

A recording from Keith R. Holden, M.D. and Paul Cobbin's live video

Dec 2, 2025 • Keith R. Holden, M.D. and Paul Cobbin

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November 2025

Join Me And Paul Cobbin Tonight In Substack Live

Paul Cobbin of “Decode Your Diagnosis” and I talk about prostate cancer in a Substack Live video this evening at 7 PM EST.

Nov 24, 2025 • Keith R. Holden, M.D.

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My PSA Doubling Time Has Drastically Slowed - 069

For seven years, my prostate cancer grew at a rapid rate with a prostate-specific antigen (PSA) doubling time (PSADT) of just 9 months.

Nov 5, 2025 • Keith R. Holden, M.D.

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September 2025

Decipher Prostate Biopsy Report Explained - 068

The test report for the Decipher Prostate Biopsy provides a three-tiered Decipher genomic score reflecting the tumor’s biological risk for distant…

Sep 23, 2025 • Keith R. Holden, M.D.

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Seven Essentials: What a 22-Gene Decipher Score Means For You - 067

A test called a Decipher Genomic Classifier is shedding light on the heterogeneity of prostate cancer, offering a clearer picture by analyzing the…

Sep 10, 2025 • Keith R. Holden, M.D.

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