This interests me. FYI, this is my story. Following a RARP in 2019, I reached BCR with a 2.0 PSA in 2022. A PSMA PET revealed a met on my left sacrum. I opted to have SRT using PBT at the Roberts PB Center at UPenn. They radiated the met on my sacrum, my iliac chain, and my prostate bed during thirty-four PBT sessions. My PSA dropped to nearly undetectable. My PSA began to rise again. it is now 3.02. I have had three PSMA PET scans and none have resulted in any dye uptake or identified mets. Hmm? I have a growing nodule in my left lung. A year ago, the nodule was 7mm and now it is 20 mm. Maybe PCa? Who knows? It is not indicated to be PCa according to its lack of dye uptake during the PSMA PET scans. I will have a FDG PET scan shortly. I cannot have the nodule surgically removed because I am being treated for ILD. My pulmonologist and medical oncologist fear that surgery involving my compromised respiratory system might tip me into further respiratory failure possibly causing permanent lifetime incubation. Not good. So, it appears that I will return to UPenn to have the nodule radiated with PB treatments. I have not used any HT nor had chemotherapy treatments nor do I want to begin those treatments. Iāll be 78 years old next month.
Iām curious about your PSA of 300. Have you obtained PSMA PET scans along with the MRI you mentioned? If so, would it be correct to assume that the PSMA PET scan radioactive dye failed to uptake and reveal any mets?
Hi JP. You are correct. My October PSA was 308 and my October PSMA PET CT showed no uptake. In addition, the CT portion showed no masses, lymphadenopathy, or bone lesions. That was the third PSMA PET CT in a series since May 2023 that showed no malignancy. My next PET CT will be in April, probably an Axumin scan. Keith
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Thanks so much James!
Hi Dr. Holden,
This interests me. FYI, this is my story. Following a RARP in 2019, I reached BCR with a 2.0 PSA in 2022. A PSMA PET revealed a met on my left sacrum. I opted to have SRT using PBT at the Roberts PB Center at UPenn. They radiated the met on my sacrum, my iliac chain, and my prostate bed during thirty-four PBT sessions. My PSA dropped to nearly undetectable. My PSA began to rise again. it is now 3.02. I have had three PSMA PET scans and none have resulted in any dye uptake or identified mets. Hmm? I have a growing nodule in my left lung. A year ago, the nodule was 7mm and now it is 20 mm. Maybe PCa? Who knows? It is not indicated to be PCa according to its lack of dye uptake during the PSMA PET scans. I will have a FDG PET scan shortly. I cannot have the nodule surgically removed because I am being treated for ILD. My pulmonologist and medical oncologist fear that surgery involving my compromised respiratory system might tip me into further respiratory failure possibly causing permanent lifetime incubation. Not good. So, it appears that I will return to UPenn to have the nodule radiated with PB treatments. I have not used any HT nor had chemotherapy treatments nor do I want to begin those treatments. Iāll be 78 years old next month.
Hi JP. If youād like to correspond with me in private, my email address is krholden@gmail.com
Keith,
Got it. thanks.
Dr. Holden,
Iām curious about your PSA of 300. Have you obtained PSMA PET scans along with the MRI you mentioned? If so, would it be correct to assume that the PSMA PET scan radioactive dye failed to uptake and reveal any mets?
Thanks,
JPD
Hi JP. You are correct. My October PSA was 308 and my October PSMA PET CT showed no uptake. In addition, the CT portion showed no masses, lymphadenopathy, or bone lesions. That was the third PSMA PET CT in a series since May 2023 that showed no malignancy. My next PET CT will be in April, probably an Axumin scan. Keith